The FDA Approves Jevtana (Cabazitaxe) For Use After Chemotherapy Failure

Hot off the press- The U.S. Food and Drug Administration (FDA) has approved Sanofi-Aventis SA's new chemotherapy drug for advanced prostate cancer. The drug, Jevtana (cabazitaxe) extended by nearly 2-1/2 months the lives of men with prostate cancer tumors that resist standard treatment with hormones as well as chemotherapy. The drug will be used after [...]

The Question, When to Use A Treatment & What Drugs Should Be Combined?

The approval of Provenge has once again brought to the forefront the very important questions about the proper timing of treatments as well as the issue concerning how to combine therapies to maximize survival. We have, although there numbers are limited, different treatments that are used for the treatment of advanced prostate cancer, but we [...]

Impact of Androgen Blockade on Overall Survival – Is There Any and When Should We Start?

For years there remains this terrible hidden question, does an androgen blockade (ADT) provide any survival advantage to men with early advanced prostate cancer? We do know that ADT will have a significant negative impact on ones life, this is guaranteed. We do know that if we go on a blockade our life will change. [...]

Risk of Thromboembolic Diseases in Men with Prostate Cancer

We all have been warned about the potential risk that hormone therapy (ADT) can cause to our heart and vascular health. A report from Lancet Oncology confirmed that men with prostate cancer living in Sweden when on hormonal therapies significantly increase their risk for experiencing a thromboembolic disease event. […]

Tasquinimod – An Anti-Angiogenesis Drug That Delays Prostate Cancer Progression

Johns Hopkins, Roswell Park Cancer Institute and Duke University have announced data at the ASCO meeting in Chicago from a 200 man phase II clinical trial of a blood vessel-blocking drug called tasquinimod. This “anti-angiogenesis” drug constricts the blood supply to prostate tumors by blocking new blood vessel development. The study showed that tasquinimod slowed [...]

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