One of the unsettled debates in our advanced prostate cancer world surrounds the issue of continuous vs. intermittent hormone therapy (IHT). Traditionally, hormone therapy was continuous, or once you started you never stopped the treatment. As many of us know, hormone therapy is notorious for damaging the quality of life. Hot flashes, loss of libido, [...]
A small phase III, randomized, double blind, placebo controlled trial of Gabapentin which looked at the Management of hot flashes in men on a hormone blockade (ADT) was recently completed and published in the March 2009 journal of the Ann of Oncology. One of the most common and bothersome side effects of a hormone blockade [...]
One of the significant secondary side effects resulting from of our advanced prostate cancer treatments can be blood clots. Blood clots are potentially dangerous as they can lead to heart attacks, strokes and death. Warfarin is one of the drugs commonly prescribed to prevent these dangerous blood clots from ever forming. However, dosing of Warfarin [...]
A graduate student, Patrica Ames, has requested that I announce her request for subjects to participate in a study she is performing about clinical trial participants. Here it is: Invitation: Hello. I am reposting this request for volunteers to help me with my PhD research. I am very grateful that some have already spent the [...]
The occasionally discussed, but not often used, alternative hormone therapy, transdermal estrogen might be ready to soon move on to a phase III trial. A poster presentation of a phase II trial showed that transdermal estrogen patches drove down testosterone and PSA levels to a similar extent as an LHRH analog. The poster presentation was [...]