In the United Kingdom cancer patients who are terminal have the opportunity to take experimental drugs long before they would be allowed to in the United States. The UK Department of Health has authorized a network of 19 hospitals where patients who have no other hope of a cure can agree to take drugs which [...]
I want to share some of the issues that I have with the FDA and the processes it uses for drug and treatment approval. The FDA demands that a drug, to show efficacy, be tested first in animal models that often are not relevant to humans. Then when the drugs are approved for human trials, [...]
On the close horizon is a new drug that will treat the many side effects of a hormone blockade (ADT). On Monday, positive results of a phase III clinical trial of toremifene citrate was released to the press. GTX Inc. (GTXI), the biopharmaceutical company that has been conducting the trial says that by this coming [...]
Protox Therapeutics Inc. (TSX-V:PRX), a Canadian biotech company, announced that it will proceed with one of three scheduled Phase 2a clinical trials evaluating PRX302 for the treatment of localized recurrent prostate cancer. Protex has begun the process of patient screening for the trial. The Phase 2a study is designed to optimize dosing in order to [...]
From clinical cancer research: Rethinking Therapeutic Cancer Vaccine Trials Ongoing therapeutic cancer vaccine trials have yet to show evidence of vaccines spurring a patient's immune system to shrink tumors -- yet patients who receive these vaccines in trials tend to live longer and respond better to subsequent treatment. In the July 1 issue of Clinical [...]