Apatone- Vitamin C & Vitamin K3) Effects PSAV And PSADT

We are constantly being bombarded with information about nutrition and supplements. Sometimes an item will foster prostate cancer and sometimes we hear that the very same item will help prevent prostate cancer. Then there are those items that will initially prevent pc, but also encourage metastatic spread of an existing tumor. It is confusing and [...]

GVAX, A Potential Immunotherapy May Be On The Horizon

I want to apologize because I have not posted anything in the last few days. I thank the few people who sent an e-mail expressing concern. On Friday evening I flew to San Diego with my wife to participate in the American Association of Cancer Researchers (AACR) Scientist-Survivor program. It is a really fantastic program [...]

Surrogate Endpoints – What They Are & Why They Are Important

On the Prostate Problems Mailing List there has been some recent discussion and a large amount of confusion expressed about the need for and importance of surrogate end points for drug and treatment approval. I attempted to make a very simple clarification and recommendation about surrogates. Here it is, but slightly modified ……. Maybe I [...]

Clinical Trials – What The Terminology Means

Sometimes when I write posts I do not stop to think if everyone understands all of the terms I use. It recently came to my attention that not everyone understands all the terminology used about clinical trials. I thought that I would define the most common terms used. Preclinical or Laboratory Studies These studies are [...]

Abiraterone Acetate (CB7630)

A recent announcement about the once daily oral drug abiraterone acetate (CB7630) indicated that some of the current trial results demonstrate some efficacy in men with hormone refractory prostate cancer. The positive results appeared at two different stages of the standard treatment process. Positive results were demonstrated both before and after the administration of chemotherapy. [...]

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