Proper Warfarin Dosing – Using Genetics

One of the significant secondary side effects resulting from of our advanced prostate cancer treatments can be blood clots. Blood clots are potentially dangerous as they can lead to heart attacks, strokes and death. Warfarin is one of the drugs commonly prescribed to prevent these dangerous blood clots from ever forming. However, dosing of Warfarin [...]

A Request for Study Subjects

A graduate student, Patrica Ames, has requested that I announce her request for subjects to participate in a study she is performing about clinical trial participants. Here it is: Invitation: Hello. I am reposting this request for volunteers to help me with my PhD research. I am very grateful that some have already spent the [...]

Estrogen, An Alternative Hormone Deprivation Drug

The occasionally discussed, but not often used, alternative hormone therapy, transdermal estrogen might be ready to soon move on to a phase III trial. A poster presentation of a phase II trial showed that transdermal estrogen patches drove down testosterone and PSA levels to a similar extent as an LHRH analog. The poster presentation was [...]

Positive Results from a Phase I-II Trial of MDV3100, Perhaps a New Alternative Hormone Blockade Option

There has been some positive news coming out of the ASCO conference in Florida this past week. One of the most significant pieces of positive news deals with the results of a phase I-II trial of the drug known as MDV3100. Basically, more than half of subjects in the study with castration-resistant prostate cancer responded [...]

Why Participate in a Clinical Trial, They Are Never Successful

Why should I participate in a clinical trial? If I participate in a trial I take a risk and probably the trial will fail to prove that there is a better drug or treatment, so why should I put myself at risk with no chance of anyone getting any benefit? This is an excellent question [...]

Go to Top