Clinical Trials

Algeta, Completing A Successful Phase II Trial For Men With Bone Metastases Will Begin Enrolling US Survivors Into A Phase III Trial

Algeta ASA (OSE: ALGETA), has announced that it will begin to enroll US survivors into its Alsympca phase III trial evaluating Alpharadin (radium-223). Alpharadin is designed to be used as a treatment for bone metastases in prostate cancer survivors with hormone-refractory prostate cancer (HRPC). The announcement of the trial follows a successful end-of-phase II meeting [...]

By Malecare|2021-02-17T10:45:20-05:00February 4th, 2009|Advanced Prostate Cancer, Alpharadin (radium-223), Clinical Trials, Clinical Trials, Metastases, Research, Uncategorized, Understanding APC|0 Comments

A Clinical Trial : Ixabepilone, Mitoxantrone, and Prednisone in Treating Patients with Metastatic Prostate Cancer That Did Not Respond to Hormone Therapy and Chemotherapy

I was recently reviewing current clinical trials and came across this one for men who have failed chemotherapy, what many of us view as the final treatment for advanced prostate cancer. It provides a potential opportunity to combine two different therapy agents (one old, mitoxantrone; one relatively new, ixabepilone). Both of these chemicals are known [...]

By Malecare|2020-02-04T10:11:12-05:00February 2nd, 2009|Advanced Prostate Cancer, Chemo Therapy, Chemo Therapy Failure, Clinical Trials, Clinical Trials, Uncategorized|7 Comments

Advanced Prostate Cancer Vaccine Being Developed in Cuba

For those of us who believed that we are alone in the search for a prostate cancer vaccine for advanced prostate cancer, the good news is that we are not. The Vladimir Ilich Lenin hospital, located in Cuba, has announced that they will shortly begin the second phase of the clinical trial of a vaccine [...]

By Malecare|2009-01-27T11:40:46-05:00January 27th, 2009|Advanced Prostate Cancer, Clinical Trials, Clinical Trials, Drugs & Treatments, Politics of Cancer, Uncategorized, vaccines|0 Comments

Gabapentin to Treat Hot Flashes

I suffered with significant hot flashes when I was on androgen deprivation therapy (ADT). I experienced between seven to 15 flashes in a twenty-four hour period. Often the flashes were accompanied with breathing difficulties and fatigue. My quality of life was significantly negatively affected. The flashes were significant enough to require that I occasionally change [...]

By Malecare|2009-01-21T12:55:41-05:00January 21st, 2009|Advanced Prostate Cancer, Clinical Trials, Clinical Trials, Hormone Therapy, Research, Uncategorized, Understanding APC|0 Comments

An NCI Clinical Trail After Chemotherapy Has Failed

What do advanced prostate cancer survivors do once we fail chemotherapy? At this time there are no FDA approved next steps other than to take some time off and pray that restarting chemotherapy will again help us. To put in another way, we wait to die. There is a huge need to find additional strategies [...]

By Malecare|2020-02-04T10:39:41-05:00January 8th, 2009|Advanced Prostate Cancer, Chemo Therapy, Chemo Therapy Failure, Clinical Trials, Clinical Trials, Uncategorized|0 Comments

Dutasteride (Avodart) Provides No Clinical Benefit to Men with Recurrent Castrate Resistant Prostate Cancer

At the University of New Mexico School of Medicine in Albuquerque, New Mexico (SKS) the Department of Urology just completed a study that showed that dutasteride, the generic name for a dual 5alpha-reductase inhibitor made by GlaxoSmithKline and marketed under the name Avodart™ in the US and Avolve™ in Europe, when administered to men with [...]

By Malecare|2020-02-04T09:03:39-05:00December 27th, 2008|Advanced Prostate Cancer, Clinical Trials, Clinical Trials, Drugs & Treatments, Hormone Therapy, Uncategorized, Understanding APC|0 Comments

So, What Happened In The Clinical Trial?

There is a lot of pressure on cancer survivors to participate in clinical trials. Without the brave individuals willing to participate in the trials research would grind to a halt along with new, improved treatments for all cancers. Even though an estimated 2.3 million people in the United States take part in clinical trials every [...]

By Malecare|2017-10-19T10:56:32-04:00December 12th, 2008|Advanced Prostate Cancer, Advocacy, Clinical Trials, Clinical Trials, Politics of Cancer, Uncategorized|0 Comments

Prominent Attorney with Terminal Cancer Gets Tysabri After Biogen Idec’s Earlier Denial- Its Implications for Prostate Cancer Treatment

A prominent attorney, Frederick Baron, who is dying of bone marrow cancer, has been granted his wish, to receive the drug Tysabri. After significant wrangling, The FDA and the Mayo Clinic found a legal basis to give him the drug in an emergency situation, even though Tysabri is not approved for any cancers. This decision [...]

By Malecare|2017-10-19T10:56:55-04:00October 22nd, 2008|Advanced Prostate Cancer, Advocacy, Clinical Trials, Drugs & Treatments, Uncategorized|0 Comments

Interim Phase II Results Support A Positive result Of CB7630 (Abiraterone Acetate) In Advanced Prostate Cancer Patients

Today, Cougar Biotechnology, Inc. (NASDAQ:CGRB) unveiled the results from its ongoing Phase II clinical trial drug CB7630 (abiraterone acetate). The data was presented at the Prostate Cancer Foundation Scientific Retreat in Lake Tahoe, Nevada. The clinical trial, which is centered at the M.D. Anderson Cancer Center in Texas and was designed to look at the [...]

By Malecare|2017-10-19T10:56:55-04:00October 21st, 2008|Advanced Prostate Cancer, Chemo Therapy, Clinical Trials, Drugs & Treatments, Research, Uncategorized|0 Comments

The Sorry State Of Affairs With Advanced Prostate Cancer Research

I extracted the following from a news release published today about a new potential vaccine therapy for advanced prostate cancer. My reason for republishing it is not for the informational value, but is to share my feelings about the sorry state of prostate cancer treatment. Please read the press release and then my comments that [...]

By Malecare|2017-10-19T10:56:59-04:00October 7th, 2008|Advanced Prostate Cancer, Clinical Trials, FDA, How We Live, Uncategorized, Understanding APC|2 Comments