Chemo Therapy Failure | malecare.org

Impact of Prior Abiraterone Acetate (Zytiga) on Subsequent Activity of Docetaxel (Chemotherapy) in Men with Metastatic Castration-Resistant Prostate Cancer

The explosion of new therapies for men with metastatic castration resistant prostate cancer (mCRPC) raises serious questions about the optimal sequencing of these new treatments as well as whether cross-resistance occurs between these drugs. It was recently reported that chemotherapy with docetaxel (D) is not effective in in men who did not have a ? [...]

By Malecare|2017-10-19T10:48:29-04:00April 1st, 2014|abiraterone acetate, Advanced Prostate Cancer, Chemo Therapy, Chemo Therapy Failure, Cross Resistance, Drugs & Treatments, Uncategorized, Understanding APC, Zytiga|0 Comments

Xtandi Shows Activity in Men with Prostate Cancer Resistant to Chemotherapy and Zytiga

Since its FDA approval in 2011 FDA abiraterone (Zytiga) has supplanted docetaxel (chemotherapy), other than perhaps Provenge, as preferred first-line treatment for metastatic castrate-resistant prostate cancer. August 2012 saw the FDA approval of enzalutamide (Xtandi) for the treatment of castrate-resistant prostate cancer after chemotherapy. Researchers performed a retrospective chart review at a large medical oncology [...]

By Malecare|2017-10-19T10:48:35-04:00February 13th, 2014|abiraterone acetate, Advanced Prostate Cancer, Chemo Therapy, Chemo Therapy Failure, Drugs & Treatments, enzalutamide, Provenge, Uncategorized, Xtandi, Zytiga|0 Comments

Correcting the NICE Guidance for Xtandi – It is worse for Men with Progressive Advanced Prostate Cancer

After a great deal of confusion and what turned out to be an error on my part I wish to let you know that the NICE (The U.K.’s National Institute for Health and Care Excellence) Guidance I shared on the blog on January 28, 2014 (http://advancedprostatecancer.net/?p=4360 ) about enzalutamide (Xtandi) was not accurate. In my [...]

By Malecare|2020-02-04T08:50:07-05:00February 5th, 2014|abiraterone acetate, Advanced Prostate Cancer, Advocacy, Cabazitaxel, Chemo Therapy Failure, Drugs & Treatments, Enzalutamide (MDV-3100), Politics of Cancer, Uncategorized, Xtandi, Zytiga|2 Comments

PLATO – A New Phase 4 Clinical Trial Extending the Use of Xtandi & Combining It with Zytiga

The makers of Enzalutamide (Xtandi), Astellas Pharma US, Inc and Medivation, Inc have begun a Phase 4 clinical trial known as PLATO. The study is designed to evaluate the efficacy and safety of continued treatment with enzalutamide (Xtandi) plus abiraterone acetate (Zytiga) and prednisone as compared to treatment with Zytiga and prednisone alone in men [...]

By Malecare|2017-10-19T10:49:16-04:00November 13th, 2013|abiraterone acetate, Advanced Prostate Cancer, Chemo Therapy Failure, Clinical Trials, Clinical Trials, Drugs & Treatments, enzalutamide, Fail First Therapy, step therapy, Uncategorized, Understanding APC, Xtandi, Zytiga|0 Comments

Living Through Chemo with the Support of Natural Immune System Boosts – Probiotics

Mama might have been correct, eat your yogurt. Many of us already know that a healthy gut with plenty of probiotics to support your gastrointestinal health is absolutely critical to boosting your immune system. Experts say that gut flora could account for as much as 80% of our immune system! A study from the University [...]

By Malecare|2017-10-19T10:49:30-04:00September 11th, 2013|Advanced Prostate Cancer, Chemo Therapy, Chemo Therapy Failure, Diet and Supplements, Drugs & Treatments, General Information, How We Live, Uncategorized, Understanding APC|1 Comment