Start A Cure Successfully Funds Its First Project – A Disparities Research Project from Johns Hopkins University

When I opened my computer this afternoon I checked the Malecare prostate cancer crowd-funding site to see how things were going. To my great pleasure I discovered that Start A Cure (www.StartACure.org) had achieved it first funding success! Sometime in the early afternoon some very kind individual made the pledge that completed the funding goal [...]

Using Circulating Tumor Cells as a Prognostic Tool – Better than PSA

Better prediction tools to predict treatment outcome in men with metastatic castration-resistant prostate cancer (mCRPC) should significantly improve treatment outcomes. Without good predictive measures we often don't know when is the optimum time to stop a therapy and move to another. This means that we might maturely stop an effective treatment losing the effectiveness of [...]

A Caution About Yesterday’s Post About Combining Treatments with Chemotherapy

My post to this blog that was written yesterday indicated that for certain men the early use of chemotherapy (docetaxil) could provide significant life extending benefits, especially for men with very advanced prostate cancer. For the purpose of clarification, in this case early use means in men who are still hormone responsive. Given that chemotherapy [...]

Early Chemotherapy for Men Who Are Still Hormone Responsive – For Some It Might Offer Extra Survival

When I was first diagnosed with metastatic prostate cancer one of the first questions that I asked my doctor was whether it made sense for me to start chemotherapy immediately. I very clearly remember him telling me that there was absolutely no evidence that starting chemotherapy at this early stage would do anything to extend [...]

Does Debulking A Tumor When Initially Diagnosed with Advanced Prostate Cancer Offer An Advantage?

Men initially diagnosed with advanced prostate cancer often face a serious question, whether traditional primary treatments that would remove or make smaller their primary tumor (“debulking” the tumor) provide any advantage or extend their survival. Since the most commonly used method to debulk tumors is surgery or radiation the question becomes if the risks of [...]

A Healthy and Happy Thanksgiving Day Each Day of the Year

To all of my American readers and anyone else who celebrates, I wish you a healthy and happy Thanksgiving.  To those of you who do not celebrate Thanksgiving Day,  I want to point out that it  can still  be a time that is important for  all of us.  It's always good to take time, take [...]

A First Victory in Our Fight Against Fail First Therapy – Thanking Health Partners in Minnesota for Their Concern for Men with Advanced Prostate Cancer

Fail First Therapy or Step Therapy has been a topic I have written about in prior posts. It is my considered opinion that as it works its way into the treatment protocols for advanced prostate cancer it will have nothing but a very negative result for our health and longevity. What is Fail First Therapy [...]

A Personal Story with A Solution to An Uncommon Side Effect From Xtandi

I was lucky enough to have a consultant here in the UK who was able to get me Enzalutamide (Xyandi) on a compassionate use basis. It worked well for some six months for which I am very thankful but I suffered from an unusual, though listed, side effect. Apart from fatigue, which seems to be [...]

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