About Malecare

Malecare is the world's leading men's cancer support and advocacy nonprofit organization.

It’s Only About Who You Love and Who Loves You

Suzanne Somers is a well known actress and also a well known cancer survivor. Her book, "Knockout: Interviews with Doctors Who are Curing Cancer and How to Prevent Getting it in the First Place" has made a very positive impression on many people, including many doctors who have strongly objected to her writings. I want [...]

Great Video Worth Spending the 9 Minutes Required Discussing Provenge and the Use of Zytiga (Along with Prednisone)

OncLive Peer Exchange has put out a video about the issues that most concern many of us surrounding the use of Provenge (Sipuleucel-T).   The video is a 9 minute discussion with Drs. Raoul Concepcion (moderator), Leonard Gomella, Lawrence Karsh, Evan Yu and Mark Scholtz.  They examine the concern that so many men with advanced prostate [...]

Establishing the New Normal After Cancer – Real Life Experiences In A Not So Normal World

According to Albert Camus, “Nobody realizes that some people expend tremendous energy merely to be normal.” The transition from patient under active treatment to being just an everyday cancer survivor can be a most challenging experience for many of us.   Our surgical scars and the radiation burns have subsided and those that remain are [...]

The Differences in Ketoconazole & Abiraterone (Zytiga)

Zytiga  (abiraterone acetate) and Ketoconazole (keto) are both widely used in prostate cancer therapy to treat men with advanced prostate cancer.   They both have a common mechanism of action, they both work by inhibiting the enzyme CYP17 that is responsible for androgen biosynthesis (creation).  Inhibiting CYP17 lowers testosterone levels, which results in prostate cancer tumor regression. Because [...]

Changes in Clinical Trials – The Addition of Patient Reported Outcomes

Recently,  the U.S. Food and Drug Administration (FDA), has begun to support the reporting and use of patient-reported outcome measures (PROMs) of symptoms as secondary end points in clinical trials for oncology treatment.  These outcomes measures are likely to become increasingly important for oncology patients as they will hopefully become part of the  drug label. [...]

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