Malecare, Author at malecare.org

Large Data Analysis Finds That Intermittent Hormone Therapy Is Equal to Continuous Therapy for Men Who Are Good Initial Responders

The Journal of Clinical Oncology, published an article by Niraula et al. that searched the general literature published through August 2012. They searched MEDLINE, EMBASE, the Cochrane Library, as well as most major conference proceedings. Their criteria for inclusion included randomized, controlled trials of intermittent hormone therapy (IADT) as compared to continuous hormone therapy (CADT) [...]

By Malecare|2017-10-19T10:49:58-04:00April 30th, 2013|Advanced Prostate Cancer, Drugs & Treatments, General Information, Hormone Therapy, Prostate Ponderings, Research, Uncategorized, Understanding APC|0 Comments

CHMP Makes A Positive Recommendation on the Use of Xtandi

The European Medicines Agency's Committee for Medicinal Products for Human Use (CHMP) has granted approval of Xtandi in the treatment of men with castrate resistant prostate cancer that has progressed after the use of chemotherapy. It has already been approved for use in the United States. Xtandi (aka Enzalutamide and MDV3100) is a strong androgen [...]

By Malecare|2017-10-19T10:49:59-04:00April 29th, 2013|Advanced Prostate Cancer, CHMP, Drugs & Treatments, enzalutamide, Enzalutamide (MDV-3100), MDV3100, Uncategorized, Xtandi|2 Comments

Teleconference – A New PROSPECT for Prostate Cancer Patients this Tuesday at 6 p.m.

Malecare will be holding a free teleconference this Tuesday, April 30 at 6.m. I will be speaking with Dr. James Gulley who is the Deputy Chief of the Laboratory of Tumor Immunology and Biology at the National Cancer Institute and the Director of the Clinical Trials Group. He also serves as a Senior Investigator within [...]

By Malecare|2013-04-26T15:03:25-04:00April 26th, 2013|Advanced Prostate Cancer, Drugs & Treatments, Firmagon (degarelix), ipilimumab, MDV3100, NIH, Prostate Ponderings, Provenge, Research, Uncategorized, Understanding APC, vaccines, Xtandi, Yervoy, Zytiga|9 Comments

Bayer Healthcare and Algeta Disappoint & Let Men with Advanced Prostate Cancer Down

The committee to start the early access clinical trials for drugs and treatments for men with advanced prostate cancer has been very hard at work. Based on the leadership and tenacity of Jan Manarite of the Prostate Cancer Research Institute (PCRI) we have managed to encourage, beg and cajole a number of pharmaceutical (pharma) companies [...]

By Malecare|2013-04-23T17:37:07-04:00April 23rd, 2013|Advanced Prostate Cancer, Alpharadin (radium-223), Clinical Trials, Clinical Trials, Drugs & Treatments, Early/Expanded Access Programs, Uncategorized|1 Comment

Why Prostate Cancer that is Hormone Resistant Still Responds to Hormone Manipulation

I don’t understand why if I have hormone resistant advanced prostate cancer why the new drugs, Zytiga and Xtandi work. These drugs are still hormone therapies, is my prostate cancer hormone resistant? I recently received an email asking me this question and I thought it might be a question many people have, so I am [...]

By Malecare|2017-10-19T10:50:00-04:00April 19th, 2013|2nd line hormone therapy, abiraterone acetate, Advanced Prostate Cancer, Drugs & Treatments, Enzalutamide (MDV-3100), Hormone Therapy, MDV3100, Uncategorized, Understanding APC, Xtandi, Zytiga|2 Comments

On The Horizon- MRI Guided Ultrasound Ablation of Prostate Cancer Tumors

In 1999 there was a new company started, InSightec, when GE Healthcare and Elbit Medical imaging joined their technologies to develop and manufacture non-invasive magnetic resonance (MRI) guided focused ultrasound technologies. The company has been in the process of developing a system that combines MRIs with ultrasound to non-surgically destroy fibroids and tumors. The company [...]

By Malecare|2020-02-04T11:55:03-05:00April 18th, 2013|Advanced Prostate Cancer, Drugs & Treatments, Imaging, Metastases, On The Horizon, Uncategorized|0 Comments

Confronting The Terror in Boston – What It Could Mean for Us

We all know about the terror that has struck Boston. Two bombs exploded near at the finish line of the Boston Marathon, killing three people and seriously injuring over 150 other individuals! One of the dead was an eight-year-old child. I know when I heard about the death of the child I prayed that this [...]

By Malecare|2017-10-19T10:50:01-04:00April 16th, 2013|Advanced Prostate Cancer, General Information, How We Live, Inspiration, Pain, Uncategorized, Understanding APC|0 Comments

An Alternative to Radiation for Pain Relief Of Painful Bone And Soft-Tissue Tumors – Microwave Ablation

Currently as our advanced prostate cancer progresses and we develop bone and soft tissue tumors our pain increases significantly. Current treatment options for the palliation of this pain includes painkillers (including opioids and methadone), radiation and in rare incidents surgery. All of these options have significant limitations. Drugs eventually become less effective, especially for breakout [...]

By Malecare|2017-10-19T10:50:01-04:00April 15th, 2013|adjuvant therapy, Advanced Prostate Cancer, Clinical Trials, Clinical Trials, Drugs & Treatments, On The Horizon, Pain, Research, Uncategorized, Understanding APC|0 Comments

Barvarian Nordic Provides A Long Anticipated Update on Their Randomized Phase 3 trial of Prostvac VF

Barvarian Nordic (BN) released some outstanding news a few days ago. According to BN they hope to complete the enrollment in their phase 3, double blind, randomized, placebo controlled, international clinical trial of their cancer vaccine, Prostvac VF. The trial known as PROSPECT is scheduled to be completed with in the next 12 months, unless [...]

By Malecare|2020-02-04T11:06:32-05:00April 12th, 2013|Advanced Prostate Cancer, Clinical Trials, Clinical Trials, Drugs & Treatments, FDA, General Information, Prostvac, Provenge, Uncategorized, Understanding APC, vaccines|2 Comments

Prognostic Significance of the PSA Nadir Level after ADT for Prostate Cancer

Having your advanced prostate cancer progress to becoming castrate resistant is a major moment in our life. For many of us becoming castrate resistant signals a major change, a foreshadowing of what the future holds. Becoming castrate resistant heralds our eventual decline which can only lead us to one destination, our demise. How long it [...]

By Malecare|2017-10-19T10:50:02-04:00April 9th, 2013|Advanced Prostate Cancer, biomarkers, General Information, Prostate Ponderings, Research, Uncategorized, Understanding APC|0 Comments

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