Malecare

The Potental Use of Dutasteride in the Treatment of Hormone Refractory Prostate Cancer

Common practice is to treat men with advanced prostate cancer with androgen inhibition therapy (ADT) with or without antiandrogens (Casodex). Most of our prostate cancer will progress and develop into androgen-independent prostate cancer despite our achieving castrate testosterone levels. Dutasteride, a 5-alfa-reductase inhibitor, is commonly used in the treatment of benign prostatic hyperplasia (BPH). Additional, [...]

By Malecare|2017-10-19T10:57:31-04:00July 2nd, 2008|Advanced Prostate Cancer, Drugs & Treatments, Hormone Therapy, Research, Uncategorized, Understanding APC|0 Comments

Clinical Trials Using Ipilimumab (MDX-010) – A New Prostate Cancer Vaccine

See the end of this post for information about additional trials that are using Ipilimumab and currently recruiting men with hormone refractory prostate cancer. A multi-site PHASE I study with 33 men has found that a drug called Ipilimumab, also known as MDX-010, has been shown to be able to stimulate the body's own immune [...]

By Malecare|2020-02-04T10:38:10-05:00June 30th, 2008|Advanced Prostate Cancer, Clinical Trials, Uncategorized|9 Comments

Cough, Cough I Forgot What I Was Going To Say!

Highlights of the advance prostate cancer session meeting in Orlando, Florida included Abstract 531 which evaluated 6,437 men who had received androgen deprivation therapy for more than 1.5 years. According to the abstract Dementia and COPD were the main non-GU side effects associated with long-term androgen deprivation. Presented by Ziya Kirkall, MD, at the Annual [...]

By Malecare|2008-06-29T18:30:50-04:00June 29th, 2008|Advanced Prostate Cancer, Drugs & Treatments, Hormone Therapy, Uncategorized|0 Comments

Men With Low Testosterone Die Sooner – What Is The Implications For Men On An Androgen Blockade?

"All-cause mortality” or death by all causes has been shown to increase in men who have deficiencies of testosterone. A new study, conducted in Germany, recently came to this conclusion. In this study, The Study of Health in Pomerania (SHIP), the researchers looked at death rates from any cause in almost 2,000 men aged 20 [...]

By Malecare|2008-06-27T13:09:34-04:00June 27th, 2008|Advanced Prostate Cancer, Hormone Therapy, How We Live, Uncategorized|0 Comments

Caution- Estrogen Helps Drive An Aggressive type of Prostate Cancer

Researchers at Weill Cornell Medical College, New York, have found the hormone estrogen plays a major role in about half of all prostate cancers. Their findings were published in the May 27 online edition of the Journal of the National Cancer Institute. They have found that the estrogen-linked signaling helps drive a discrete and aggressive [...]

By Malecare|2017-10-19T10:57:33-04:00June 26th, 2008|Advanced Prostate Cancer, Prostate Ponderings, Research, Uncategorized|0 Comments