There are different methods of performing ADT; these methods include continuous or intermittent as well as differences in the actual blockade itself. Understanding the superior schedule as well as the superior combination of drugs can both delay the onset to castrate resistance as well as provide for a longer overall survival (OS). In a research [...]
On March 4, 2014 I wrote a post “Castrate Resistant Prostate Cancer- What to Do Next” (www.advancedprostatecancer.net/?p=4425). The basic theme of the post was about how difficult it is to know how to sequence the new drugs we have to treat advanced prostate cancer (metastatic castrate resistant prostate cancer aka mCRPC). In the post I [...]
Satraplatin is an oral platinum drug that is believed to bind the DNA of the cancer cell, which then prevents the cancer from being able to reproduce. Satraplatin had been tested in a phase III trial in men with metastatic castrate-resistant prostate cancer (mCRPC) who have failed chemotherapy with docetaxel. It failed because it did [...]
Confusion, confusion and more confusion, that is how I would describe the current decision making process for a man with prostate cancer that has become newly castrate resistant. Just a few years ago the decision tree was clear, castrate resistant, immediately on to chemotherapy with docetaxel. Today, in this treatment space, we have a number [...]
It has been announced by the International Strategic Cancer Alliance that a Dutch university that intends to launch global trials has purchased the Combidex technology. Combidex is a scan contrast that periodically gets discussed among prostate cancer survivors, but it has not been available for a few years. It is an injectable nanoparticle fluid (contrast) [...]
The commonly used serum (blood) marker for inflammation is C-reactive protein (CRP). It is believed that CRP has a prognostic impact for men with metastatic prostate cancer (MPC) (advanced prostate cancer). The researchers conducted a meta-analysis to quantitate its prognostic impact. They conducted asystematic review to identify publications and presentations exploring the association of baseline [...]
Today’s New York Times Science Times section had a very interesting article written by Tara Parker-Poe about Male breast cancer. As her opening line of the article went, “Breast cancer is not always pink.” She wrote about a photography series recently mounted that feature the faces and scars of men with breast cancer. The photos [...]
The best way to understand your PSA kinetics, especially its changes, is to be able to visualize them on a graph. This allows you to understand significant changes in our PSA earlier on than you might otherwise perceive them. Any man whether diagnosed with prostate cancer or not should be recording their PSA scores and [...]
It has been accepted that Zoledronic acid (ZA)(Zometa) reduces the onset risk of skeletal-related events (SRE) caused by bone metastasis in prostate cancer as well as improving their quality of life (QOL). ZA has become a standard supportive therapy for men with prostate cancer who have bone metastasis. However, there is an issue which I [...]
Malecare has recently launched a newsletter specifically about advanced, metastatic prostate cancer. This is the only Newsletter in publication that is dedicated exclusively to advanced prostate cancer. Everything in the newsletter is about advanced prostate cancer and every article is actionable by you. The Newsletter is about things that you can use today to improve [...]
