Viagra May Protect Heart from Damage Caused by High Blood Pressure

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“First evidence that the Impotence Aid Helps a Signaling Protein Protect the Heart”

Written by J. Strax, psarising.com.

“The first direct evidence in lab animals that the erectile dysfunction drug Viagra (sildenafil) amplifies the effects of a heart-protective protein has been reported today by a team of researchers at three leading US medical centers, Johns Hopkins in Baltimore, Tufts Medical Center in Boston and University of North Carolina.

“Published in the Journal of Clinical Investigation online, the findings help explain why sildenafil has already been shown to improve heart function and may one day have value in either treating or preventing heart damage due to chronic high blood pressure.

“The key, investigators say, is sildenafil’s effects on a single protein, RGS2, newly identified in the latest study as an essential link in the chain reactions that initially protect the body’s main blood-pumping organ from spiraling into heart failure.

“Experimenting in mice, the team of heart experts first established that after a week of induced high blood pressure, the hearts of animals engineered to lack RGS2, or regulator of G-protein signaling 2, quickly expanded in weight by 90 percent. Almost half the mice died of heart failure. In mice with RGS2, by contrast, the dangerous muscle expansion, known as hypertrophy, was delayed, growing only 30 percent, and no mice died.

“Subsequent tests treating hypertensive mice that had RGS2 with sildenafil showed enhanced buffering, with less hypertrophy, stronger heart muscle contraction and relaxation, and as much as 10 times lower stress-related enzyme activity compared to their untreated counterparts. In mice lacking RGS2, sildenafil had no effect.

“Sildenafil clearly prolongs the protective effects of RGS2 in mouse hearts,” says study senior investigator and cardiologist David Kass, M.D.”

By | 2017-10-19T10:56:29+00:00 January 5th, 2009|Healing the Mind, Sexuality and Intimacy|2 Comments

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2 Comments

  1. High Blood Pressure January 5, 2009 at 9:05 pm

    Great post, I agree with this article. With this drug researchers finds new treatment and agent to lower blood pressure to those who are suffering hypertension. And it is safe and has a protective effects of RGS2. Thank you for sharing. Cheers.

  2. Leah January 6, 2009 at 9:31 am

    I don’t think Viagra is said to lower blood pressure, just to protect the heart from the effects of it.

    Leah

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